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Professor David Nutt has spent a career making the argument for a rational, evidence-based approach to drug policy and drug use. The scientific evidence still challenges perceived wisdom on drugs and for that reason can appear to be contentious. In this podcast, the Professor explores the actual harms and potential benefits of various drugs, challenging myths surrounding classification and legislation, and exploring the societal impact of poorly informed drug policy. Using evidence in public ...
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The Drug Discovery World Podcast

Drug Discovery World (DDW)

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Here at Drug Discovery World (DDW) we've been publishing articles written by leading experts in the Drug Discovery, Pharmaceutical, and BioPharmaceutical industries for over 20 years. DDW has grown as a quarterly business review of drug discovery and development, and now we've created this podcast to allow you to listen to our articles on the go. In our journal and this podcast, we cover topics surrounding: drug discovery; drug development; business; chemistry; enabling technologies; informa ...
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Hello Combi-Nation! Our industry fee complicated sometimes. Drugs, devices, clinical trials, submissions, sterilization validation, design control, risk management, market access reimbursement, the list goes on. My name is Subhi Saadeh. I've spent over a decade in medical device, pharma, and combination product development. My goal is mastery, so this podcast is to ask questions I have to people who may have the answers. Whether you're background is Pharma, Device or both, I invite you to li ...
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FDA Drug Safety Podcasts

U.S. Food and Drug Administration, Center for Drug Evaluation and Research

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FDA Drug Safety Podcasts, produced by FDA's Center for Drug Evaluation and Research, provide emerging safety information about drugs in conjunction with the release of Drug Safety Communications. For more information, please visit: www.fda.gov/drugsafetypodcasts
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Cowboy Junkies have been making music since 1986, when they released their debut album "Whites Off Earth Now!!" More than 35 years later, they are still producing compelling albums and taking that music on the road - pandemics permitting... In this series, the band talk you through their songs, one by one, digging deep into each of them, from right across their career. www.cowboyjunkies.com www.latentrecordings.com
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Welcome to Drugs & Stuff. We're a podcast about drugs, harm reduction, mass criminalization, the drug war, and other stuff from the Drug Policy Alliance (DPA) – the nation's leading organization working to end the war on drugs. We bring in a wide variety of experts – from scientists to activists, writers to teachers – to hear about how drugs and drug policy play a role in their work and lives. We also offer a peek behind the scenes as we feature DPA staff talking about the work they do.
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Welcome to ”The Business of Drug Development Operations Podcast” hosted by Sheila Mahoney-Jewels, a seasoned professional in the pharmaceutical industry. In this insightful podcast, Sheila explores the dynamic and complex world of drug development operations, offering a unique perspective on the business aspects that drive innovation in the pharmaceutical field. From navigating regulatory landscapes to optimizing clinical trial processes, each episode delves into the challenges and opportuni ...
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News From The Drug War Front is a weekly radio show that seeks to explore the failure of the "The War on Drugs", or more appropriately the "The War On People Who Take Drugs". Prohibition has countless negative effects on society has a whole and unfairly damages individuals use drugs already marginalized. NFTDWF aims to change peoples minds by informing and educating listeners about the failure and moral bankruptcy that is the faled experiment, "The War On Drugs". NFTDWF is aired on Tuesdays ...
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On September 28, 2012, Massachusetts state chemist Annie Dookhan was arrested and charged with obstruction of justice and falsification of academic records. Approximately four months later another chemist, Sonja Farak, was arrested for using the drugs she was supposed to be testing and the Massachusetts Drug Lab Scandal was born. Hosts Jamie Folk and Ilyas Rona will be exploring the William H Hinton, UMass Amherst and State Police crime labs associated with this scandal and speak with the la ...
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On this episode I was joined by Captain Alan Stevens, Global Head of Complex Devices and Drug Delivery Systems at AbbVie. In this episode, Alan walks through: 00:38 Exploring Reliability in Combination Products 01:17 The Importance of Subscribing and Feedback 01:36 Alan Stevens Shares His Expertise 02:40 Understanding Reliability: Definitions and N…
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In this episode, we meet with Dr. Suresh Muthukumaraswamy, an Associate Professor of Pharmacy in Auckland. Dr. Muthukumaraswamy discusses his early research, exploring the functional connectivity of substances like DMT and Ketamine. He proceeds to share insights into his breakthrough realisation regarding the disparity between the self-reported suc…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. From a weight loss drug that prevents heart attacks and a gene therapy that restores hearing, to a vaccine that can treat viruses that don’t…
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On this episode I was joined by Chuck Ventura, Founder of Ventura Solutions and CEO of HemoTek. On this episode Chuck walks through: 00:29 Design Changes When No DHF Exists 03:30 Challenges and Strategies in Document Management 04:49 Improving Design Inputs and Risk Management 21:37 Leveraging Tools for Better Traceability and Compliance Charles Ve…
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In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Tien Lee, CEO of Aardvark Therapeutics, a San Diego-based biotech company in Phase II studies of its drug, ARD-…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. A leading news story this week has been the announcement of positive Phase II results of a head and neck cancer trial, but there have been a…
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On this episode, I was joined by Tony Watson, Vice President of Regulatory and Quality at Windgap Medical. On this episode, Anthony discusses: 03:11 The Formation and Impact of the Office of Combination Products 04:16 Challenges and Changes in the Regulatory Landscape for Combination Products 07:53 Understanding FDA Titles and Organizational Struct…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The ongoing innovation and development in the drug discovery sector relies on a number of moving parts, one of which is financial support an…
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Professor Mitul Mehta explains how his studies in neuroscience and the role of dopamine in learning and memory led to his own career in neuroimaging. He offers an overview of what neuroimaging entails and how these scans can contribute to the advancement of research. Drawing from his latest research centred around Schizophrenia, Mitul delves into o…
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On this episode, I was joined by Richard Koch, Founder of KochSaMD. Richard discusses: 00:29 Exploring Software's Role in Medical Devices 02:29 Deep Dive into Cloud-Based Medical Devices 06:29 The Intricacies of Software Development in Medical Devices 26:33 The Future of Medical Devices in the Cloud Era 32:56 The Potential Impact of Tech Giants on …
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In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Steve Worland, CEO of eFFECTOR. eFFECTOR is a company targeting three distinct targets central to the eIF4F tra…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The leading news story this week has been the launch of a new clinical trial in the UK for a melanoma personalised mRNA cancer vaccine, but …
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This is the latest episode of the free DDW narrated podcast, titled “A look behind the scenes of the drug discovery industry” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Going paperless – the move to electronic lab notebooks, New horizon for cancer innovation, and A personal touch: the role of bioprinting …
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On this episode, I was joined by Devon Campbell, Founder, Prodct LLC + CPO, myBiometry.Devon discusses: 02:20 The Journey to Consulting: A Year of Saying No 03:09 Advising Startups: The Role of a Consultant 05:08 The Shift to Consulting: Embracing Joy and Impact 09:21 Navigating the Startup Ecosystem: Challenges and Opportunities 13:31 Building a P…
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In this episode, Prof Neill and Dr Thurgur meet with Dr Gül Dölen, a neuroscientist known for studying social behaviour and psychedelic drugs. Together, they explore the role of critical periods in trauma and mental health; following the potential of Psychedelics in reopening critical periods which were previously thought to be closed, they debate …
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The headline news this week all concerns clinical trials for new drugs that could have a significant impact on future patient treatment, inc…
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On this episode, I was joined by Leo Eisner "IEC 60601 Guy", Founder of Eisner Safety Consultants. On this episode, Leo discusses: 00:56 Evolution of Industry Standards 02:00 The Impact of Standards on Medical Device Development 02:10 Standards and Regulatory Challenges 02:42 Standards in Medical Devices and Emerging Technologies 13:19 The Auditing…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The cancer research news has been coming thick and fast from the American Association of Cancer Research (AACR) Annual Meeting in San Diego …
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On this episode, I was joined by Jeanne Moldenhauer, Vice President at Excellent Pharma Consulting. Jeanne and I discuss:- Assessing Drugs, Devices, and Combination Products for Sterility Methods- Regulatory Frameworks and EMA's Decision Tree (Link)- Novel Methods: liquid phase sterilization, ionization, physics based sterilization, high pressure s…
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In this episode, Prof Nutt meets with German author Norman Ohler as he speaks about his new book “Tripped” which addresses drug use in post-Nazi Germany. Ohler shares how a secret history held back therapeutic research of psychedelic drugs for decades and eventually Nazi policies became part of the foundation of America’s War on Drugs. Ohler discus…
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On this episode I was joined by Aaron Snyder, VP of Quality Assurance at Allotex. Aaron discusses: 00:58 Exploring the Impact of QMSR on Medical Device Companies 02:19 UDI Regulations 05:18 Understanding the FDA's Approach to QMSR and Compliance 18:02 The FDA's Inspection Techniques and the Future of QMSR 31:55 Where to Find Aaron and Closing Thoug…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In another busy week for drug discovery and development, we have seen the FDA approval of a monoclonal antibody for emergency use in Covid-1…
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On this episode I was joined by Captain Alan Stevens, Global Head of Complex Devices and Drug Delivery Systems at AbbVie. In this episode, expect to learn from Alan about how reliability engineering concepts can be used for single use combination products. Why infusion pumps are susceptible to recalls. Why people call Allen captain Allen Stevens. A…
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On the 100th Episode of the Drug Science podcast, Prof David Nutt meets with Dr James Rucker to celebrate the 100th anniversary of Maudsley Hospital. James shares his experiences as one of the first clinicians in a psychedelic study hosted by David Nutt before explaining his own personal journey into psychedelic research. Starting from a PhD in Gen…
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This is the latest episode of the free DDW narrated podcast, titled “Flow cytometry for drug discovery research” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Flow cytometry technologies and cancer associated fibroblasts and Leveraging flow cytometry in drug discovery. In the first article, Dr Amber Miller, …
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On this episode, I was joined by Former FDA Investigator and Managing Consultant of Practical Compliance Results, Vin Cafiso. Vin discusses: 01:35 Journey from Premed to FDA Investigator: VIN's Story 07:25 Understanding the Impact of QMSR on Industry 16:24 The FDA's Approach to Inspections and Compliance 27:45 The Shift Towards Quality Culture in F…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Following the recent AD/PD 2024 conference, which took place on 5-9 March in Lisbon, Portugal, there have been a number of key announcements…
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On this episode I was joined by Naveen Aggarwal founder of Creative Analytic Solutions and host of "Let's talk risk". In this episode, Naveen walks through the big changes to risk management with the QMSR, and risk beyond safety. The episode covers the confusion surrounding the mandatory nature of risk management in particular and we spend the seco…
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In this episode, we meet with Jane Slater, co-founder of Anyone’s Child and Anne Marie, a mother who tragically lost her child, Martha, to an accidental overdose. Anne and Jane discuss the consequences of drug policy failures and the need for safe drug use education, drawing in on Anne’s personal journey. She discusses the pain of losing a loved on…
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In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Ahmed Mousa, CEO of Vicore Pharma. Vicore Pharma is exploring the potential of a new class of drug candidates, …
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. It was antibodies hitting the headlines this week, with the discovery of antibodies with potential against a new influenza target, the launc…
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On this episode I was joined by Mat Straton, Founder of Coalition Ltd. In this episode, Mat discusses: 01:02 Venturing into Combination Products 02:46 Andy's Journey into Healthcare Space 04:48 Challenges in Deep Brain Stimulation 08:55 The Impact of working with Andy Grove 10:42 The Struggle with Parkinson's Disease 13:20 The Speed of Product Deve…
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This is the latest episode of the free DDW narrated podcast, titled: What trends will speed up the journey from clinic to bedside? It covers three articles written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Sitting down with… PharmEnable, Is single-cell gene expression the next trend in next generation sequencing? and Preparing for…
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On this episode, I do an active reading to begin to unpack the Quality Management System Regulations(QMSR) Final Rule that was issued by FDA in early February 2024. 0:00 Introduction 05:09 Initial Reactions to the idea of the QMSR 06:57 History of the Device cGMP's, QSR, and QMSR 11:52 What's changing in 21 CFR 820? 24:59 What's changing in 21 CFR …
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In this week's episode, we feature John Marks, an Addiction Psychologist who spearheaded the Merseyside experiment in northwest England from 1982 to 1995. Throughout this 13-year period, Marks fearlessly operated clinics in Liverpool, basing his practice on the long-term maintenance prescribing of opiates to opiate users. The high media profile of …
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In a breakthrough for advanced therapies, this week saw the FDA approve the first ever cell therapy for solid tumour cancers, but there were…
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In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Quin Wills, Co-founder and CSO of Ochre Bio, a company whose scientists are working in collaboration with AI to…
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In this episode, I talk with Steve Rader from NASA's Center for Excellence. Steve, an Open Talent advocate, explores how NASA's innovation aligns with pharmaceutical, given shared traits like confidentiality and regulations. Despite challenges, NASA taps into 'the power of the crowd.' Join us for insights on NASA’s 'Future of Work,' overcoming outd…
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On this episode, I was joined by Andy Robertson, founder of CQE Academy. In this episode, Andy outlines 5 steps to becoming an exceptional quality engineer, such as seeking mentorship, taking on challenging assignments, and being a lifelong learner. Andy stresses the importance of honing soft skills for effective leadership and suggest stepping out…
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The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week our news highlights focus on skin conditions, with positive updates on hidradenitis suppurativa, systemic sclerosis, wound-healing…
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On this episode, I was joined by Peter Baker, President @ Live Oak QA. The conversation revolves around the speaker's experience working with the FDA, starting from his time in San Francisco and culminating in his experiences in international locations like India and China. The discussion outlines the FDA's diverse focus areas, from food to medical…
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In this episode, we meet with Patrick Cox, a fashion designer with a background collaborating with Vivienne Westwood. Patrick shares his personal journey from his lifestyle in fashion, led to confronting deep-seated intergenerational trauma. Patrick opens up about undertaking the highly secretive Hoffman Process, and the transformative impact this …
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For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode five, Solving the diagnostic odyssey with multi-omics. Catherine Brownstein is an Assistant Professor in Pediatrics at Harvard Medical School …
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On this episode, I was joined by Jim Fries, CEO of Rx360. On this episode, Jim discusses the critical aspects of audits in medical technology and pharmaceutical sectors. He provides insight into the joint audit program that RX-360 rolled out, its working, and benefits. He addresses the challenges faced, emphasizing the need for relationship buildin…
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For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode four, The building blocks of AI success stories. Dr Mike Tarselli, Chief Scientific & Knowledge Officer at TetraScience, was Scientific Direct…
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Listen to FDA Drug Safety Podcast titled, FDA adds Boxed Warning for increased risk of severe hypocalcemia in patients with advanced chronic kidney disease taking osteoporosis medicine Prolia (denosumab).
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For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode three, Connecting academia, industry and the public. Erin Welsh, PhD, is a disease ecologist and epidemiologist now working full-time as a sci…
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For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode two, Where is the Ignite Theater tech leading us? At this year's SLAS event, DDW has curated a track taking place in the Ignite Theater, spons…
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For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode one, called, “A welcome to SLAS 2024”, which includes two comment pieces. Thomas wrote the first one, “The journey from lab to patient”, which…
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On this episode, I was joined by Sayed Badrawi, Pharma/MedTech Investor and Board Member. Sayed walks through starting at Amgen as a bench scientist and transitioning to the commercial side of the Pharma industry. Sayed provides advice for people considering their career paths and emphasizes the importance of gaining expertise in a particular area …
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