Najlepsze podcasty z kategorii: AMiNDR (2024)

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341 - Prevention & Intervention Strategies for AD 46:41

8M ago46:41

46:41

Naila brings you 21 articles from January 2024, on non-pharmacological approaches to the prevention and intervention of Alzheimer's disease. You'll be treated to research from computational modeling, to rodent models, to clinical trials, with a particular focus on optimizing and personalizing intervention strategies. This episode also covers some r…

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340 - Structure Neuroimaging in Alzheimer's Disease using AI 31:26

8M ago31:26

31:26

Join Christy for 12 papers from January 2024 on structural neuroimaging in the diagnosis of Alzheimer's disease. This episode is a bit different from past ones because it's all about the use of machine learning and deep learning. Whether you're an AI researcher or simply curious about the topic, you won't want to miss this episode. Detecting AD (3:…

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339 - Treatments Targeting Neuroprotection in Alzheimer's Disease 19:10

8M ago19:10

19:10

Another series of AMiNDR kicks off with this episode. Anusha takes you through 7 papers published in January 2024 targeting neuroprotection in AD. If you'd like to hear about potential compounds that could reduce neurodegeneration in Alzheimer's disease, this is the episode for you. Testing for neuroprotection in cell lines (2:57) Testing for neuro…

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338 - Interview with Joseph Liang - Navigating The Journey To (And Through) Graduate School 24:44

9M ago24:44

24:44

Another special episode to help kick off our return! In what we hope to be a recurring special series, an interview with members in our scholarly community on navigating the multiple facets of life as a scientist. In the first episode, host Kevin Nishimura interviews one of our own Joseph Liang on his personal journey to and through graduate school…

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337 - Prevention & Intervention Strategies for AD 29:29

10M ago29:29

29:29

In today's episode, Naila provides an overview of 14 articles published in November 2023 on non-pharmacological interventions for AD. You'll hear about cognitive training, music therapy, chair yoga, providing support to caregivers, and a range of neural stimulation techniques. Enjoy! Cognitive and Social Factors (2:26) Lifestyle interventions (13:4…

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336 - Treatments Targeting Cholinergic Neurotransmission in AD 29:24

10M ago29:24

29:24

Join us as we cover a set of papers published in November 2023 on treatments targeting cholinergic transmission in Alzheimer's disease. In this episode hosted by Christy, we will go over various topics, from drug discovery using synthesized compounds to drug testing of plant extracts, as well as improving drug delivery through the blood-brain barri…

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335 - A Conversation with Gina Martin: Bringing Visual Awareness to Dementia 52:00

10M ago52:00

52:00

As we get back up to speed on our regular episodes, we thought we'd treat you (and ourselves) to something out of the ordinary: a conversation on how visual storytelling can shape how we think - and feel - about Alzheimer's disease. Host Naila Kuhlmann had the pleasure of interviewing Gina Martin, who founded the Bob and Diane Fund to support and p…

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334 -Treatments Targeting Neuroprotection in Alzheimer's Disease 27:07

10M ago27:07

27:07

Hello listeners, it’s been a while since we last released an episode but we are back with another series here at AMiNDR bringing you a synopsis of publications on Alzheimer’s disease (AD) research on various topics that were released in November of 2023. In this episode, Anusha takes you through 11 papers testing potential neuroprotective agents fo…

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333 - Cognitive & Behavioural Changes in Alzheimer's Disease: February 2023 19:40

1+ y ago19:40

19:40

If you’re interested in hearing about the impact of hearing aids on quality of life in AD patients, or how having a stable life partner can slow down the progression of dementia, tune in to this episode on the latest in cognitive and behavioural research in Alzheimer's disease! Judy will cover 9 papers on sleep, depressive symptoms and sensory proc…

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332 - Prevention & Intervention Strategies for Alzheimer's Disease: February 2023 27:24

1+ y ago27:24

27:24

In today's episode, Naila provides you with an overview of 10 paper published in February 2023, on non-pharmacological therapies for Alzheimer's disease. You'll learn about a virtual reality intervention targeting anxiety, the signaling pathways underlying the potential benefits of acupuncture, the challenges of implementing new interventions, and …

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331 - Treatments Targeting Neuroprotection in Alzheimer's Disease: February 2023 23:15

1+ y ago23:15

23:15

This short and sweet episode kicks off the February 2023 series, highlighting studies all the way from worms to humans. Anusha will take you through 9 papers that converge on targeting neuroprotection in Alzheimer's disease. If you're interested in learning about implicated pathways or potential therapeutics, this episode is sure to whet your appet…

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330 - Vascular Changes in Alzheimer's Disease: January 2023 40:12

1+ y ago40:12

40:12

Elyn's back with more insight from the field on how blood vessel health impacts brain health. Tune in for a journey through mechanisms underlying increased risk from "vascular risk factors" like hypertension, diabetes, and atrial fibrillation, lots of neuroimaging studies providing clinical insights, and several interesting novel therapeutic avenue…

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329 - Treatments Targeting Neurotransmission in Alzheimer's Disease: January 2023 22:21

1+ y ago22:21

22:21

This episode covers some papers from January 2023 on treatments focused on repairing the neurotransmitter imbalance in Alzheimer's disease. We hope you enjoy listening as Christy summarizes this exciting research—from the discovery of new therapeutics to the synthesis of drugs. Sections in this episode: Drug Screening (3:37) New Drugs (7:00) Synthe…

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328 - Functional Connectivity & Imaging in Alzheimer's Disease: January 2023 32:25

1+ y ago32:25

32:25

In today’s episode of AMiNDR, Ellen will tell you all about the functional connectivity of different networks in the brain, and changes to brain structure and volume in Alzheimer’s disease. This includes how these changes in the brain relate to cognitive changes, behavioural symptoms, and other neuropathological markers. There are many fascinating …

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327 - Prevention & Intervention Strategies for Alzheimer's Disease: January 2023 30:05

1+ y ago30:05

30:05

Naila covers 11 papers from January 2023, with a focus on a variety of stimulation techniques. You'll get a smattering of new research from humans to mice to flies, and from brain imaging to computer simulations to molecular mechanisms. Enjoy! Sections in this episode: Complementary therapies (2:55) Current and magnetic stimulation (7:25) Electroac…

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326 - Cognitive & Behavioural Changes in Alzheimer's Disease: January 2023 25:08

1+ y ago25:08

25:08

We’ve got a whole variety of studies in this January 2023 episode, spanning from sensory processing, to sleep, and even to depressive symptoms. Tune in to learn more about the latest in cognitive and behavioural changes in Alzheimer's disease! Sections in this episode: Sensory Processing (2:28) Sleep (7:30) Balance (14:14) Depression (17:00) Other …

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325 - Treatments Targeting Neuroprotection in Alzheimer's Disease: January 2023 39:56

1+ y ago39:56

39:56

In this episode, we’ll be covering papers that were released in January 2023 that target neuronal and synaptic protection in Alzheimer’s Disease. If you’re interested in the preclinical testing of novel therapeutics and delivery methods, this is the episode for you! Sections in this episode: Novel Therapeutics Targeting Neuroprotection (4:53) Novel…

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324 - Synaptic Transmission in Alzheimer's Disease: January 2023 25:44

1+ y ago25:44

25:44

We are diving in to all things neurotransmitters and synaptic signaling to kick off the January 2023 series. You'll hear about dopamine, noradrenaline, prion proteins, a new 3D cell culture model, and more, in today's episode. Enjoy! Sections in this episode: Monoamine Neurotransmitters (3:50) Glutamate (9:18) Acetylcholine (15:51) Synaptic Protein…

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323 - The Immune System & Glia in Alzheimer's Disease Part 1: November 2022 27:00

1+ y ago27:00

27:00

Welcome our new host, Anelya, who covers 12 papers on the role of immune system and glia in Alzheimer’s disease. The first half of this episode will focus on potential targets for the treatment of Alzheimer’s disease, followed by the disease-associated inflammatory mechanisms. Part 2 will be released as a bibliography. We hope you find this episode…

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322 - Functional Connectivity & Imaging in Alzheimer's Disease: November 2022 21:30

1+ y ago21:30

21:30

Ellen brings you summaries of 8 abstracts from November 2022, all about functional connectivity and imaging in the context of Alzheimer's disease. There are a variety of brain regions covered in today's episode, including cortical regions, subcortical structures, and the hippocampus. Spanning studies in both humans and animals, this episode is sure…

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321 - Prevention & Intervention Strategies for Alzheimer's Disease: November 2022 48:09

1+ y ago48:09

48:09

For today's episode, Naila is back to take you through 20 papers on prevention and intervention strategies in Alzheimer's. You'll be treated to the latest on mindfulness and meditation, the default mode network's involvement in Alzheimer's, strategies for assessing and optimizing therapies, stimulation techniques and more. Enjoy! Sections in this e…

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320 - Treatments Targeting Neuroprotection in Alzheimer's Disease: November 2022 25:46

2y ago25:46

25:46

In this episode, Anusha guides you through 11 papers that were published in November of 2022. These papers study the efficacy of treatments targeting neuroprotection in Alzheimer's Disease models. Tune in if you want to be on the cutting edge of drug discovery and development in the field of AD. Sections in this episode: Drug Discovery and Developm…

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319 - Cognitive & Behavioural Changes in Alzheimer's Disease Part 1: November 2022 20:31

2y ago20:31

20:31

Judy is so excited to take you through part 1 of the behavioural and cognitive changes in AD episode (part 2 will be released as a bibliography). This shorter episode features standard motor symptoms like impaired exercise and grip strength, as well as some less studied behavioural changes such as adverse driving in AD. You don’t want to miss this …

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318 - Synaptic Transmission in Alzheimer's Disease: November 2022 26:31

2y ago26:31

26:31

Ellen kicks off the November 2022 series with 11 papers about synaptic transmission and neurotransmitters in Alzheimer's disease. Hear about glutamate, acetylcholine, synaptic proteins, and more in this jam-packed episode! Sections in this episode: Glutamate and Acetylcholine (4:01) GABA neurons (10:52) Neuron Excitability (12:15) Synaptic Proteins…

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317 - Functional Connectivity & Imaging in Alzheimer's Disease: October 2022 23:46

2y ago23:46

23:46

Today, we talk all about neuroimaging, with 7 papers that use various imaging modalities in humans, animals, and computational modeling, to study how the brain changes in Alzheimer’s disease. Tune in to learn more! Sections in this episode: Hippocampus (3:50) Hypothalamus (8:15) Cortical regions (10:29) Nucleus basalis (15:57) Pineal gland (18:40) …

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316 - Treatments Targeting Neuroprotection in Alzheimer's Disease: October 2022 31:24

2y ago31:24

31:24

Anusha brings you another episode of AMiNDR featuring literature published in October 2022. In this episode, you'll hear 12 papers that converge on the topic of treatments that target neurotoxicity. This episode is poised to leave you feeling hopeful about the various treatment avenues to be pursued so be sure to tune in! Sections in this episode: …

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315 - Cognitive and Behavioural Changes in Alzheimer's Disease: October 2022 26:50

2y ago26:50

26:50

In today's episode, there's a big focus on sleep in Alzheimer's disease, as well as other clinical and pharmacological studies that dive into the cognitive and behavioural deficits. We even have one paper that looks into character strengths in AD, so definitely join Judy and follow along in this unique episode from our October 2022 series! Sections…

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314 - Vascular Changes in Alzheimer's Disease: October 2022 30:30

2y ago30:30

30:30

In this episode, Elyn takes you through 13 papers from October 2022 published on vascular contributions to Alzheimer disease. It's quite the journey through mechanistic mouse studies, neuroimaging studies, and a few studies assessing treatments targeting the vasculature, which all paint a pretty convincing picture of the importance of the cerebrova…

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313 - Synaptic Transmission in Alzheimer's Disease: October 2022 13:39

2y ago13:39

13:39

Kick off the new year with Ellen, who tells you all about synaptic transmission in Alzheimer's disease in this episode. You'll hear about 5 papers published in October of 2022 on synaptic transmission, ranging from research on whole brain networks all the way down to individual proteins. -------------------------------------------------------------…

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312 - Prevention & Intervention Strategies for Alzheimer's Disease: August 2022 37:06

2y ago37:06

37:06

We have one last episode for you to wrap up 2022! In this episode, Naila will guide you through 11 papers published in August 2022, covering a range of way researchers are working on preventing or treating aspects of Alzheimer's disease through non-pharmacological therapies. You'll hear about cognitive training tools, the effects of disrupting circ…

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311 - Understanding APOE: August 2022 28:08

2y ago28:08

28:08

In this month's episode of AMiNDR, Cassi recaps papers on APOE published in August 2022. Cassi just defended her dissertation where she studied immunometabolism in the context of APOE. She starts with cells, moves to mice, and finishes with human research studies. -------------------------------------------------------------- To find the numbered b…

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310 - Cognitive and Behavioural Changes in Alzheimer's Disease: August 2022 20:34

2y ago20:34

20:34

Today, we have papers on behavioural and cognitive changes in Alzheimer’s disease. We’ve got our usual sections such as rodent models and sleep, but we also have some new topics, including cognitive reserve and even a paper on virtual reality. You’re in for a treat! Sections in this episode: Behavioural Changes (2:28) Cognitive Changes (11:10) ----…

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309 - Vascular Changes in Alzheimer's Disease: August 2022 27:30

2y ago27:30

27:30

After a bit of a break, Elyn is excited to be back with the latest in the field of vascular contributions to Alzheimer disease. With the current (and constant) controversy in the field about targeting amyloid as a disease-modifying therapy, perhaps it's time we turned to a new target: the vasculature. Tune in for an overview of papers published in …

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308 - Synaptic Transmission in Alzheimer's Disease: August 2022 16:46

2y ago16:46

16:46

To kick off our series on August papers, we will talk all about different ways that synaptic transmission may be affected in Alzheimer's disease, with 6 research papers that use either cell models, animal models, or human patients. Stay tuned! Sections in this episode: Cortical signaling in rodent models (3:15) New AD models (8:32) Biomarkers of ne…

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307 - Cognitive & Behavioural Changes in Alzheimer's Disease Part 2: July 2022 23:24

2y ago23:24

23:24

In Part 2 of Cognitive and Behavioural Changes, Naila covers 8 papers on neuropsychiatric, social and cognitive symptoms linked to Alzheimer's disease, and their implications for diagnosis and disease management. You'll learn about the links between AD and depression, the importance of social networks, and machine learning methods for identifying i…

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306 - Prevention and Intervention Strategies for Alzheimer's Disease: July 2022 45:47

2y ago45:47

45:47

In this episode, Naila will guide you through 14 papers on potential neuroprotective factors to mitigate the risk of Alzheimer's disease, non-pharmacological interventions that could directly target Alzheimer's pathology, and strategies for symptom management. You'll hear about the role of embodiment in memory, light therapy technologies, the role …

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305 - Treatments Targeting Neuroprotection in Alzheimer's Disease: July 2022 26:47

2y ago26:47

26:47

This is an episode all about targeting synaptic and neuronal heath in Alzheimer's disease. Anusha will cover in silico, in vitro, and in vivo studies of candidate compounds that target neuroprotection and neurogenesis. Be sure to check out this paper to stay up to day on the latest preclinical therapeutics being tested. Sections in this episode: In…

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304 - Understanding APOE: July 2022 25:04

2y ago25:04

25:04

In this episode exploring the effect of allelic variation of APOE, we review abstracts from large human GWAS studies all the way down to new mouse models expressing the human ApoE proteins. There are some particularly interesting abstracts on protection from cognitive decline despite having a risk allele for Alzheimer's disease. These are great stu…

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303 - Cognitive & Behavioural Changes in Alzheimer's Disease Part 1: July 2022 14:45

2y ago14:45

14:45

Part 1 of our cognitive and behavioural changes category will focus on papers that explore behavioural and sensory processing deficits in AD. Topics range from motor impairments to visual and olfactory processing in both human patients and mouse models of AD. If you're curious about how AD patients process the facial expression of pain, then this i…

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302 - Vascular Changes in Alzheimer's Disease: July 2022 29:20

2y ago29:20

29:20

Elyn is back to discuss the latest research on vascular contributions to Alzheimer disease! Tune in to hear about proteomic changes with amyloid deposition in the vasculature, new therapeutic avenues, and a more detailed account of the perivascular space. If you're interested in factors beyond amyloid and tau in the Alzheimer disease pathology, thi…

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301 - Synaptic Transmission in Alzheimer's Disease: July 2022 30:48

2y ago30:48

30:48

We are kicking off our July 2022 series of AMiNDR with this episode and are so glad you are tuning in. If you’re interested in changes to neuronal function in AD, we’ll be covering the entire spectrum in this episode. Starting big with network changes, we scale all the way down to molecular changes that may underlie AD pathology, so if that’s what …

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300 - Prevention and Intervention Strategies for Alzheimer's Disease: June 2022 41:14

2y ago41:14

41:14

Today's episode includes 15 papers on non-pharmacological treatments and complementary therapies for AD. Naila will take you through research published in June 2022 on an array of topics including olfactory training, beer, choir participation, light therapy, and transcranial magnetic stimulation. You'll be treated to research on both the human and …

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299 - Cognitive Assessment in Alzheimer's Disease Part 2: June 2022 29:39

2y ago29:39

29:39

We promised you we would be back with more on clinical assessment for Alzheimer’s disease, and here we are to deliver. Stick around to hear about papers published in June 2022 on validating variations of the Montreal Cognitive Assessment, tracking Activities of Daily living, and digital tools for assessing cognition. Our harvest yielded 7 abstracts…

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298 - Understanding APOE and Alzheimer's Disease: June 2022 20:22

2y ago20:22

20:22

Approximately, one in every five people you know, has a copy of the largest genetic risk allele for late-onset Alzheimer's disease called apolipoprotein E4 (APOE). In this episode, Cassi discusses papers from June 2022 about APOE and covers human subjects research, pathology related to E4 risk, and mechanisms. Sections in this episode: Human Subjec…

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297 - Genetic Insights for Alzheimer's Disease: June 2022 32:41

2y ago32:41

32:41

In this episode, Joseph covers papers published in June 2022 on GWAS studies, transcriptomics, genetic and genomic studies and the like on Alzheimer’s disease. Stay tuned! Sections in this episode: Genetic & Disease Overlaps (2:15) RNA & Transcriptomics (5:10) Genetic Testing (10:25) GWAS Studies (15:24) Specific Genes (21:04) Extra (28:55) -------…

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296 - Treatments Targeting Neuroprotection in Alzheimer's Disease: June 2022 25:22

2y ago25:22

25:22

Anusha brings you 12 papers today on the development of treatments that target neuroprotection in Alzheimer's disease. This includes a range of research models, from in silico and drug discovery studies, to rodent models of AD. Enjoy! Sections in this episode: In Silico and Drug Discovery Studies (2:27) Testing Phytochemicals in AD Rodent Models (7…

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295 - Cognitive and Behavioural Changes in Alzheimer's Disease: June 2022 24:45

2y ago24:45

24:45

This episode contains a whole range of topics in cognitive and behavioural changes in AD! Tune in as Judy covers a variety of papers published in June 2022, spanning from from sensory processing in mouse models to antidepressants in human patients. There's bound to be something that piques your interest! Sections in this episode: Studies Using Mous…

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294 - Cognitive Assessment in Alzheimer's Disease Part 1: June 2022 35:08

2+ y ago35:08

35:08

You are here, with us, right now, about to get the updates you eagerly wait for every month in Alzheimer’s disease research. A whole episode dedicated to assessing neurocognitive domains for screening and diagnostics. Learning and memory? Executive function? Perceptual and motor skills? You got it! 7 abstracts published in June 2022, nicely package…

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293 - Vascular Changes in Alzheimer's Disease: June 2022 28:07

2+ y ago28:07

28:07

Ever thought there was more to Alzheimer disease than the plaques and tangles? You've come to the right place. Join Elyn for a guide through the latest research on vascular contributions to Alzheimer disease. June 2022 brought lots of new insight into how vascular hallmarks interact with the classic AD hallmarks to influence cognition, emphasis on …

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292 - Synaptic Transmission in Alzheimer's Disease: June 2022 17:53

2+ y ago17:53

17:53

We are kicking off our June 2022 series of episodes with this short and sweet episode. Anusha takes a look at papers published on the subject of changes to synaptic transmission and neuronal excitability in Alzheimer’s disease. If you're interested in bridging the gap between changes to neuronal function and behavioural consequences, this episode i…

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