Michael Levin & Mustafa Djamgoz | Bioelectricity and Cancer

Live Longer World

This interview is part of my series with Dr. Michael Levin where we interview significant people in the history of developmental bioelectricity. Dr. Mustafa Djamgoz was one of the first people to study the role of ion channels and bioelectricity in cancer, which he initially documented in a 1995 paper. His research showed that there was an uptake in voltage-gated sodium channels in all types of cancer metastasis, except prostate cancer, highlighting the significant role of studying ion channels in cancer. Simply put, the spread of cancer cells is linked to increased activity in sodium ion channels, which regulate electrical currents in our cells. Episode Show Notes: https://livelongerworld.com/p/mdjamgoz Find me: https://x.com/aasthajs Background on the bioelectricity series & 1st episode with Dr. Richard Nuccitelli: https://youtu.be/DtUqOwTRvz0?si=3OJryM0yJjzfQtfo TIMESTAMPS: 0:00 Playing with radios at age 17 to bioelectricity cancer research 4:31 Advice for young people entering bioelectricity 9:02 Biophysics and Cancer neuroscience 17:55 Role of bioelectricity in cancer 27:02 Cancer metastasis and ion channels 28:49 Sodium channel uptake and cancer invasiveness 36:59 Ranolazine, potential anti-metastatic drug 43:45 Funding for bioelectricity cancer research 50:21 Advice for cancer patients AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/

Instagram: https://www.instagram.com/aasthajs/ Michael Levin: https://twitter.com/drmichaellevin Mustafa's publications: https://profiles.imperial.ac.uk/m.djamgoz/publications Mustafa's book Beat Cancer: https://www.amazon.com/Beat-Cancer-Regain-Control-Health-ebook/dp/B00CU8QBAS Episode Show Notes: https://livelongerworld.com/p/djamgoz Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm