9. Debunking the Blood Sugar Myth: How Gluconeogenesis Keeps You Stable Without Constant Eating

Healthy AF | Healthy After 50

Today, we're debunking the myth that you need to eat every few hours for stable blood sugar. We'll discuss gluconeogenesis, the liver's role in blood sugar regulation, and how high-protein meals can help.

Our liver uses amino acids to create glucose, keeping blood sugar stable between meals. Surprisingly, even experienced fitness professionals may overlook this vital function. Eating a high-protein meal can provide essential nutrients and help with blood sugar management without causing spikes.

Remember the power of gluconeogenesis next time someone tells you to eat constantly to avoid blood sugar crashes!

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Episode Minute-by-Minute Recap:

• 0:02 What’s inside today’s conversation
• 0:08 The real function of the liver
• 4:35 How blood sugar and gluconeogenesis work
• 7:16 The metabolism energy needed for each macro
• 10:00 Why you always need some level of insulin in the body
• 15:47 Th difference between gluconeogenesis and eating a carb
• 18:39 How to leverage metabolic stressors correctly

Links For This Episode:

Gluconeogenesis and energy expenditure after a high-protein, carbohydrate-free diet https://academic.oup.com/ajcn/article/90/3/519/4597025

Defining gluconeogenesis https://www.ncbi.nlm.nih.gov/books/NBK541119/

Protein metabolism and effect on blood glucose https://pubmed.ncbi.nlm.nih.gov/9416027/#:~:text=Protein has a minimal effect,an elevated blood glucose level.

Aminos in gluconeogenesis https://www.sciencedirect.com/topics/neuroscience/glucogenic-amino-acids#:~:text=Amino acids that contain three,citric acid cycle or gluconeogenesis).

Gluconeogenesis citric acid cycle https://courses.lumenlearning.com/suny-nutrition/chapter/6-42-gluconeogenesis/

Role of Physiological Levels of 4-Hydroxynonenal on Adipocyte Biology: Implications for Obesity and Metabolic Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038367/

Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half Century https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4642429/

Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578804/

Fasting Hormones Synergistically Induce Amino Acid Catabolism Genes to Promote Gluconeogenesis https://www.cmghjournal.org/article/S2352-345X(21)00088-6/pdf