Najlepsze podcasty z kategorii: Michelle Whelan (2024)

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EP 119 A Beginner's Mindset in Entrepreneurship - A Gut Instinct/Rachel Castelino 32:42

4d ago32:42

32:42

In this episode, we speak with Rachel Castelino who is the founder of Blume Prebiotic Tonic), a company dedicated to promoting gut health through delicious prebiotic beverages packed with natural ingredients and plant fibre. Rachel educates us in this episode about the difference between probiotics and prebiotics and unsung hero of our body – the g…

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Glenn Auerbach: In Search of Good Sauna 51:10

4d ago51:10

51:10

In Search of Good Sauna: Heat, Tradition and Connection, with Glenn Auerbach, Founder and Editor of Sauna Times Heat is really having a moment. And not just heat, but cold, too. Saunas and cold plunges, sweat lodges, and swimming in freezing oceans. Infrared home saunas and cold showers. In the last year, all of these and more have been featured in…

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EP 150: Cracking the biological code of aging with Martin Borch Jensen, Co-Founder and Chief Scientific Officer at Gordian Biotechnology 44:21

6d ago44:21

44:21

0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…

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EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre 34:16

13d ago34:16

34:16

0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…

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EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

20d ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

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EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

27d ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

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EP 118 Lead DE&I from you Stand/Michelle Lim 43:58

28d ago43:58

43:58

In this episode, we speak with Min-Shi Michelle Lim, a former professionally trained ballet dancer, who uses her behavioural psychology and neuroscience background in the diversity, equity, inclusion and ethics space. She is well regarded for her advocacy and practitioner experience, named as one of the 40 under 40 Most Influential Asian Australian…

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EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

1M ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

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EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

1M ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

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EP 117 The Language of Chai - Identity, Integrity & Empowerment/Uppma Virdi 43:40

1M ago43:40

43:40

In this episode of Business in Colour, I talk to Uppma Virdi who is a trailblazing female entrepreneur. Just when her legal career in a disruptive start-up was about to take off, she made the decision to run her own business called Chai Walli. She built this business from the ground up, making it her and her team’s mission to preserve the Indian cu…

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EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

2M ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

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EP 116 The Rise of the Interim Executive & Power Skills/Jacinta Whelan 44:43

2M ago44:43

44:43

In this episode of Business in Colour, Sadhana and I talk to Jacinta Whelan, a partner with Watermark Executive Search. Jacinta is an award-winning author, thought leader and popular speaker on the concept of Interim Executives, Portfolio Careers and future ways of working. She leads the Melbourne office of Watermark and has over 25 years’ experien…

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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

2M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

2M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

2M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

3M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

3M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

3M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

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EP 115 The Choice to Feed Fearlessly - Mumamoo/Miriam Weir 39:38

3M ago39:38

39:38

In this episode of Business in Colour we talk to Miriam Weir who is one of four Directors and co-owners of Mumamoo, a premium, scientifically designed, grass-fed, cows milk product. Proudly South Australian owned and Australian made. They are the National Winner 2024 Accelerating Women’s category of the Telstra Best of Business Awards. Along with C…

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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

3M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

4M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

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EP 114 Active Followership & Humanistic Leadership/Lee Goddard 49:39

4M ago49:39

49:39

In this episode of Business in Colour Sadhana and I talk to Lee Goddard who was appointed as the inaugural Executive Director and CEO of the Australian Missile Corporation. He is also a Non-Executive Director of AUSTAL and the Commonwealth Superannuation Corporation, and an Advisor to the Minderoo Foundation. Prior to assuming his current industry …

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EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

4M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

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EP 113 "Act on Values, Kindness, Wise Optimism & a Very Clear Vision" /Colin Mackey 42:07

4M ago42:07

42:07

In this episode of Business in Colour, Sadhana and I talk with Colin Mackey, a mining engineer and procurement executive who has recently returned to Australia from living and working in Serbia. Colin shares the influence of his upbringing in the UK and his time working on major construction projects. We are lucky enough to have Colin walk us throu…

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EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

4M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

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EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

4M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

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EP 112 Youth-led Impact in Business /Rosie Thyer 44:39

5M ago44:39

44:39

In this episode of Business in Colour Sadhana and I chat to the inspiring Rosie Thyer Rosie is the chairperson of Culture Spring, a youth-led social agency that aims to transform organisations, institutions, and workplaces to make them more inclusive and culturally safe for Australia’s young multicultural community. Rosie taught me the distinction …

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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

5M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

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EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

5M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

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EP 111 Ask What I CAN Do - Disability & Gender Advocacy/Tricia Malowney 33:23

5M ago33:23

33:23

Tricia Malowney is a disability and gender advocate. She calls herself an accidental advocate and credits her mother for her can-do attitude and confidence. We talk about the slow progress for disability in Australia, compared to the UK. Some of the reasons Tricia cites are: the flaw in the ABS data, low funding, the low or emerging understanding o…

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EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal 51:56

5M ago51:56

51:56

Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…

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Dr. Ira Bedzow: Life on Purpose 53:41

5M ago53:41

53:41

Life on Purpose: Insights on well-being and education from Ira Bedzow, PhD, Executive Director of the Emory Purpose Project Purpose and meaning are foundational to any definition of the good life. They are also a trendy topic these days. Like all trendy topics, they risk being trivialized by our intense hunger for easy answers to life’s difficultie…

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EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy 38:44

5M ago38:44

38:44

0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…

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EP. 110 Believe in the Twenty Percent - Disability Inclusion/Emma Olivier 46:46

5M ago46:46

46:46

Emma Olivier is the founder and CEO of Twenty Percent, a Disability Advisory working with Corporate Australia. With over 30 years of consulting experience and born without a left hand, she understands from her own lived experience the challenges and opportunities of having a disability in the corporate world. This episode is packed with practical g…

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EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata 50:18

6M ago50:18

50:18

0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…

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Episode 11: Herb for HR 28:21

6M ago28:21

28:21

The squabbles, pettiness, and arguing have started at Chalkboard Learning, and for some reason Sarah is the one that seem to defuse the argues that come to her. He approach to this, is not making any situation any better and rather hide in the bathroom than to deal with it. Doug decided it time to hire on some from HR to help sort of the conflicts …

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EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin 39:10

6M ago39:10

39:10

0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…

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EP 109 Solutions for Advancing Women in STEMM 50:52

6M ago50:52

50:52

Dr. Morley Muse is a Chemical, Environmental and Renewable Energy Engineer with expertise in waste-to-energy generation, wastewater treatment, renewable hydrogen generation, biofuels production and energy transition including storage, transmission and waste heat reuse. She has worked across academia, government, and industry including in consulting…

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EP. 108 Use Your Hypervisibility/Lisa Martello 50:02

6M ago50:02

50:02

Lisa Martello is a construction project Director with a depth of experience leading high-profile rail, engineering, demolition, and construction projects in the UK and Australia. Think…bridge upgrades, tunnel ventilation projects, stations, and structures. She is also a Board Director and Chair of the Diversity & Inclusion Portfolio for the Nationa…

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EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund 39:41

6M ago39:41

39:41

0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…

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EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy 45:23

6M ago45:23

45:23

0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …

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EP 107 The Personal is Political with Gender Equity/Angela Pippos 47:55

6M ago47:55

47:55

Angela Pippos is a Journalist, TV Presenter, Radio Personality, Documentary-maker, Author and more. In this episode, Angela shares her early love of sport, being a middle child, her parent’s influence growing up in a Greek-Australian family in Adelaide. She reflects on her father’s start - cleaning the floors and being a Props Boy at Channel 7 to a…

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EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews 42:00

6M ago42:00

42:00

0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…

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EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute 45:34

7M ago45:34

45:34

0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…

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Dr. Chantelle Thomas: Sanity in the Wild New World of Psychedelic-Assisted Therapy 52:41

7M ago52:41

52:41

Sanity in the Wild New World of Psychedelic-Assisted Therapy The buzz about psychedelics is everywhere these days, especially in the mental health space, where these compounds are being hailed as the greatest potential therapeutic breakthrough of the last 50 years. What was once elemental to the hippie movement of the 60s and then stigmatized and f…

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Episode 10 - The Interns 48:43

7M ago48:43

48:43

With a fresh client on the horizon, or as Sarah phrases it, the next client in queue, ToDoBuddy prepares for upcoming builds. It appears that the team is occupied with other projects, and with the imminent launch of the last client, they opt to assign the project to the interns. Ryan and Maggie, the recent high school graduates and new interns, see…

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EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome 35:55

7M ago35:55

35:55

Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…

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EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar 44:10

7M ago44:10

44:10

Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…

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EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology 43:47

7M ago43:47

43:47

0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…

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EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan 38:25

8M ago38:25

38:25

0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…

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