EP176: State of Alzheimer's Disease Research

This Is Getting Old Podcast with Melissa B PhD

“As a nurse, I'm all about lifestyle strategies and preventing Alzheimer’s from even happening to us”

—Melissa Batchelor, PhD, RN, FNP, FGSA, FAAN

Alzheimer's disease poses a significant threat to individuals and societies worldwide due to its devastating impact on cognitive function and quality of life. Although a cure has not been found, ongoing research gives hope for better treatments to ease symptoms, slow down the disease, and make life better for people with Alzheimer's.

THE STATE OF ALZHEIMER'S DISEASE RESEARCH

Alzheimer's disease, a top 10 leading cause of death, remains a problem in medical science. Despite decades of research and billions of dollars invested, no effective prevention, treatment, or cure exists. The failure rate of clinical drug trials is staggering, with over 146 drugs failing to deliver promising results.

CHALLENGES IN DRUG DEVELOPMENT

The complexity of Alzheimer's disease poses significant challenges in drug development. Many experimental drugs fail because they either don't work or cause serious side effects. In this episode, I explain several reasons for this including misdiagnosed study participants, the impact of research focus, and more.

FUTURE DIRECTIONS OF CLINICAL RESEARCH

The future of Alzheimer's disease research lies in a multifaceted approach, targeting various aspects of the disease's pathology. New studies show that inflammation plays a big role in damage to the brain in Alzheimer’s disease, which opens up possibilities for new treatments. While clinical trials continue to face challenges, there's hope that personalized treatments and lifestyle changes can lower the risk of Alzheimer's.

HOW TO KEEP A HEALTHY BRAIN

To keep your brain healthy, proactive measures play an important role. Lifestyle strategies like managing blood pressure, maintaining a healthy weight, and engaging in regular physical activity, can significantly reduce the risk of cognitive decline. While we're waiting for breakthroughs in drug development, these strategies give us all ways we can take control of our brain health.

RESOURCES

Two great resources can help you keep your brain healthy. The AARP Staying Sharp program provides access to cognitive assessments, daily activities, and educational resources, promoting brain-healthy habits. Additionally, the Brain Health Resource Center offers comprehensive information on Alzheimer's disease and related conditions, along with free hearing tests for AARP members.

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About MelissaBPhD

Melissa Batchelor, PhD, RN, FNP, FGSA, FAAN. I am a nurse, nurse practitioner with over 25 years of experience caring for older adults and their families.

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